To set up and use QuickBooks Workforce, first, sign up for QuickBooks Online Payroll and activate the employee self-service feature. Next, invite employees to create their accounts by sending them an email invitation to join QuickBooks Workforce. Employees can then sign in to Workforce to access their pay stubs, W-2 forms, and other payroll-related information. As an employer, you can use QuickBooks Workforce to manage employee access, edit payroll data, and send messages to employees.